What the research shows

The ProvayBlue label reports data from an open-label study and an observational registry. Among 28 adults with baseline methemoglobin measurements, 26 had a drop of at least half at the first follow-up measurement. Timing varied between patients and neither study had a randomized comparison group. These results concern a blood disorder. They do not measure memory or everyday energy. Read Clinical Studies in the ProvayBlue label.

Documented formats

The label describes the finished methylene blue solution used for this indication. Laboratory staining reagents can share its chemical name while differing in concentration, additives and quality specifications.

Testing and purity

For a clinical paper, match the manufacturer and formulation to the study. For a laboratory stain, check the solvent, concentration and intended analytical use on its own specification.

How to read a batch report

Questions about Methylene Blue

Did a 50% reduction mean that half the patients improved?

It describes the change in an individual’s measured methemoglobin relative to their starting value. Twenty-six participants reached that threshold.

Why does the time of the blood test matter?

The first post-treatment measurement ranged from about 12 minutes to more than a day. Two first measurements could represent different stages of recovery.