What the research shows

Sixteen people with chronic insomnia spent five nights in a sleep laboratory. In a blinded comparison, half received synthetic DSIP and half received placebo before the final three nights. The DSIP group fell asleep sooner and spent more time asleep while in bed, while participants’ own ratings of sleep quality stayed similar. The researchers described the differences as weak and partly attributable to changes in the placebo group. Double-blind sleep-laboratory study.

Earlier investigators characterized the amino-acid sequence and compared the activity of the synthesized nine-residue peptide with the original material. Chemical characterization and synthesis of DSIP.

Documented formats

The clinical experiment used an intravenous preparation. An earlier chemical study examined the amino-acid sequence and activity of the synthetic nine-residue peptide.

Testing and purity

Look for a sequence-level match to emideltide and a record of the preparation used. A label that reads “sleep peptide” leaves the identity open.

How to read a batch report

Questions about DSIP / Emideltide

What does sleep efficiency mean here?

It is the share of time in bed spent asleep, calculated from the overnight recording. Participants separately rated how well they felt they had slept.

Could the trial tell whether the effect lasted?

The comparison covered three treatment nights. Longer-term sleep quality would require follow-up beyond that window.